Biotech & Medtech
Biotech & Medtech news — Wednesday 28 October 2026
35 stories from 5 sources, every one in English. Each links to its publisher.
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Senators Investigate Insurers’ Role in Removing Thousands from ACA Coverage
MedCity News
Democratic senators are investigating 10 insurers’ role in the Trump administration’s termination of 760,000 ACA enrollees’ coverage over suspected fraud. The post Senators Investigate Insurers’ Role in Removing Thousands from ACA Coverage…
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STAT+: Lawmaker wants government watchdog to probe TrumpRx over claims about drug savings
STAT News
A House lawmaker asked the Government Accountability Office to review whether the TrumpRx platform has saved Americans any money. In an Oct. 27 letter, Frank Pallone (D-N.J.), the ranking member of the House Committee on Energy and…
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Eli Lilly’s ‘Triple-G’ Drug Tops Ozempic in Head-to-Head Type 2 Diabetes Trial
MedCity News
Topline Phase 3 results show Eli Lilly’s retatrutide beat Novo’s Ozempic on measures of blood sugar and weight loss in adults with type 2 diabetes. Retatrutide is a peptide designed to activate three metabolic targets versus just one hit…
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STAT+: HHS moves to allow compounding of some unapproved peptides
STAT News
WASHINGTON — The Department of Health and Human Services released a policy that will temporarily allow compounding pharmacies to manufacture some peptide products, increasing access to the experimental wellness therapies embraced by many…
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Ahead of Midterms, HFMA Calls for Cross-Sector Action on Healthcare Affordability
MedCity News
With healthcare affordability set to influence voters’ decisions in next week’s midterm elections, the Healthcare Financial Management Association is calling on healthcare leaders to move beyond finger-pointing and work together to address…
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Lilly’s ‘triple-G’ drug tops Novo’s Ozempic in diabetes trial
BioPharma Dive
The highest dose of retatrutide beat Ozempic on measures of blood sugar and weight loss, but was also associated with higher side effect rates and treatment discontinuations.
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FDA unveils guidance for ‘plug and play’ gene therapies
BioPharma Dive
The plan builds on recent FDA moves to speed "personalized" treatments by offering an approval framework for therapies benefiting different subsets of patients with the same disease.
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Senate candidate El-Sayed wants to ‘grill’ RFK Jr., calls him the ‘most incompetent HHS secretary ever’
STAT News
Abdul El-Sayed doesn’t make headlines as the Senate candidate who wrote a book on applying systems science to public health , or who worked to rebuild Detroit’s health system, or who researched the ways social circumstances can impact…
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STAT+: Why every health care AI company must face Epic
STAT News
This is the web edition of STAT’s AI Prognosis newsletter, our guide to artificial intelligence in health care and medicine. Sign up to get it delivered in your inbox every Wednesday. Thanks for your suggestions for my apple-themed…
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Work Requirements Put New Pressure On Medicaid Member Retention
MedCity News
By using existing data to better understand members and implementing retention strategies, plans can remain sustainable and members can get the care they need. The post Work Requirements Put New Pressure On Medicaid Member Retention…
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STAT+: Pharmalittle: We’re reading about 340B battles, new results for a Lilly weight loss drug, and more
STAT News
Top of the morning to you. Blue skies, cool breezes, and plenty of chirping birds are enveloping the comfy Pharmalot campus, which is cause to fire up the trusty coffee kettle for a needed cup of stimulation, and we invite you to join us…
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STAT+: Lilly’s triple-G drug beats Ozempic in head-to-head study
STAT News
Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Good morning. We’ve got lots of news today to get into. Lilly’s triple-G drug beats Ozempic in head-to-head study…
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How Can Hospitals and Pharmacists Collaborate on Effective Stewardship Programs for Opioids and Antibiotics?
MedCity News
[Sponsored] A webinar sponsored by Inovalon explored how hospitals and pharmacies can work together to generate the best outcomes for patients while improving patient safety. The post How Can Hospitals and Pharmacists Collaborate on…
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Lilly shuffles business structure; Novartis writes off part of Avidity deal
BioPharma Dive
Lilly intends to merge its U.S. and international divisions when a top executive retires. Elsewhere, Astellas closed in on what it believes to be a “best-in-class” cancer immunotherapy prospect.
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What has actually caused the decline in drug overdose deaths?
STAT News
Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds. Sign up here . Good morning. We’ve got a big investigation into Epic for you today. Yes, that Epic. Refill your coffee to read the great…
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STAT+: Lilly says ‘triple-G’ drug beats Novo’s Ozempic in diabetes study
STAT News
Eli Lilly on Wednesday said that its investigational drug was more effective at lowering blood sugar and cutting weight than Novo Nordisk’s Ozempic in a large diabetes study, further boosting the competitive profile of its medicine. In the…
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Opinion: Freezing my eggs showed me just how anti-feminist the fertility industry can be
STAT News
In August, Democratic Rep. Alexandria Ocasio-Cortez’s egg-freezing journey incited a national debate about fertility and reproductive rights, with women on both sides of the aisle hailing her decision as a feminist one (amid, of course…
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Opinion: How pediatricians like me are helping families stay calm and informed about measles
STAT News
I’m a primary care pediatrician practicing in Pennsylvania. Nearly every day, I hear from parents who say: “I’m scared. How can I protect my baby from measles?” With more than 1,300 reported cases in my state, 33% in children , the threat…
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Have you been impacted by Epic’s actions?
STAT News
Epic is the largest electronic health records vendor in the United States. Its data systems, used by a majority of large health systems, hold the health information of some 8 in10 Americans. Epic’s increasing market dominance has coincided…
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STAT+: As Epic’s dominance grows, its iron grip is choking innovation in health technology
STAT News
By most measures, Epic Systems Corp. is a runaway success. Its record-keeping systems, invented at the dawn of personal computers in a Wisconsin basement, are now ubiquitous inside the nation’s largest hospitals. The company collects more…
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Dynamical coarse-graining of neural-network training
arXiv cs.NE (Neural／Bio)
arXiv:2610.36180v1 Announce Type: cross Abstract: Dynamical coarse-graining of neural networks gives macroscopic observables and enables training to be predicted, and controlled in a state space far smaller than the parameter space. In…
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Exploiting heterogeneous delays for efficient computation in low-bit neural networks
arXiv cs.NE (Neural／Bio)
arXiv:2510.27434v2 Announce Type: replace Abstract: Neural networks rely on learning synaptic weights. However, this overlooks other learnable neural parameters. One such parameter is delay: neurons communicate asynchronously with…
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GAS-PFN: Graph-Aware Spatiotemporal Prior-Data Fitted Networks for Zero-Shot Traffic Forecasting
arXiv cs.NE (Neural／Bio)
arXiv:2610.37598v1 Announce Type: cross Abstract: Traffic forecasting requires modeling complex temporal dynamics and the spatial dependencies imposed by road topology. Supervised graph-based models achieve strong performance, but are…
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Autonomous fixed-wing interception using reinforcement learning
arXiv cs.NE (Neural／Bio)
arXiv:2610.37470v1 Announce Type: cross Abstract: Medium altitude, long endurance unmanned aerial systems such as Shahed-type strike drones are an unanswered threat in modern conflicts. Conventional air defense systems are too expensive to…
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SLICE-CiM: Selective Layer-wise Inference Control Engine with Confidence-Based Early Exit for SRAM based Digital Compute-in-Memory
arXiv cs.NE (Neural／Bio)
arXiv:2610.37601v1 Announce Type: cross Abstract: Digital SRAM compute-in-memory (CIM) macros enable energy-efficient CNN inference by eliminating off-chip weight transfers; however, peripheral control logic introduces three…
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MIDAS: Mosaic Input-Specific Differentiable Architecture Search
arXiv cs.NE (Neural／Bio)
arXiv:2602.17700v2 Announce Type: replace-cross Abstract: Differentiable Neural Architecture Search (NAS) provides efficient, gradient-based methods for automatically designing neural networks, yet its adoption remains limited in practice…
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Characterizing Privacy Leakage in Spiking Neural Networks: A Systematic Analysis of Temporal Dynamics, Stochasticity, Neuronal Dynamics and Learning Mechanisms
arXiv cs.NE (Neural／Bio)
arXiv:2610.36243v1 Announce Type: new Abstract: Spiking neural networks (SNNs) encode information not only in whether neurons fire but also in when they fire, and this temporal dimension shapes what a trained network reveals about its…
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Where Should the Evaluation Budget Go in LLM-Driven Agent Scaffold Evolution?
arXiv cs.NE (Neural／Bio)
arXiv:2610.37276v1 Announce Type: cross Abstract: Large language model (LLM)-driven agent scaffold evolution improves agent workflows through iterative candidate generation and evaluation. Evaluation both guides subsequent search and…
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Provable Speedups From Dynamic Population Sizes in Evolutionary Algorithms for Multiobjective Optimization
arXiv cs.NE (Neural／Bio)
arXiv:2607.23800v2 Announce Type: replace Abstract: This paper investigates the role of dynamic population sizes in evolutionary multi-objective optimization. Although such approaches are widely used in practice, their benefits remain…
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Physiology-Informed Audio Quality and Listening Effort Estimation
arXiv cs.NE (Neural／Bio)
arXiv:2610.36865v1 Announce Type: cross Abstract: Audio systems aim to maximise the listener's perceived quality, traditionally evaluated through mean opinion scoring (MOS), a subjective process that is slow, costly, and collected only…
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When is Fine-Tuning Scalable? Certified Recovery from Noisy Data and Linear-Cost Fine-Tuning on Structured Task Shifts
arXiv cs.NE (Neural／Bio)
arXiv:2509.00924v2 Announce Type: replace-cross Abstract: Transformers often transfer across related tasks with little fine-tuning; we study this question in noisy nonparametric regression for continuous maps $f,g:[0,1]^d\to\mathbb{R}^D$…
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GNBG-C: A Unified and Configurable Benchmark Generator for Constrained Continuous Optimization
arXiv cs.NE (Neural／Bio)
arXiv:2610.37590v1 Announce Type: new Abstract: Many real-world optimization tasks are governed not only by what should be optimized, but also by what is allowed: a solution must first satisfy physical, operational, safety, budgetary, or…
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Every route counts, but some count more: a max-plus view of the C. elegans brain
arXiv cs.NE (Neural／Bio)
arXiv:2610.37587v1 Announce Type: cross Abstract: Brains do not simply add up every signal they receive: they select which routes dominate. Yet connectomes are usually analyzed with tools that sum over all paths and place neural states in…
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An mRNA–lipid nanoparticle vaccine against H5N1 influenza virus protects lactating dairy cows from infection
Nature Biotechnology
Nature Biotechnology, Published online: 28 October 2026; doi:10.1038/s41587-026-03343-6 Dairy cows are protected from H5N1 influenza by an mRNA vaccine.
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An engineered, compact Cas12m variant for multiplexed gene activation in vivo
Nature Biotechnology
Nature Biotechnology, Published online: 28 October 2026; doi:10.1038/s41587-026-03352-5 smCRISPRa is a compact platform for high-efficiency multiplexed gene activation in mouse models.