Biotech & Medtech
Biotech & Medtech news — Thursday 01 October 2026
42 stories from 5 sources, every one in English. Each links to its publisher.
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AMA: PBM Market Concentration Is On the Rise
MedCity News
The AMA found that OptumRx, Express Scripts, CVS Caremark and Prime Therapeutics controlled 75% of the national PBM market in 2024. The post AMA: PBM Market Concentration Is On the Rise appeared first on MedCity News .
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STAT+: Medicare Advantage plans shift more costs onto seniors in 2027
STAT News
People who have a Medicare Advantage plan — and wind up needing care and prescriptions next year — are in for a rude awakening. Medicare Advantage insurers are raising out-of-pocket costs for enrollees, drastically cutting money for dental…
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Sanofi Puts Up $1B to Expand Regeneron Alliance and Develop Next-Gen Dupixent
MedCity News
Sanofi and Regeneron Pharmaceuticals will collaborate on four next-generation antibody drugs that could offer advantages over Dupixent, the blockbuster immunology drug spawned by their R&D alliance. The companies project these drugs will…
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Top journal’s special issue on women’s health casts spotlight on menopause and pain
STAT News
Ovulation. Endometriosis. And especially: menopause. These once taboo words — among others — have become part of our daily vocabulary and conversations, a sign of greater interest in, and knowledge of, women’s health. Yet even as women’s…
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Mistrust in science and a juicy gene-editing lawsuit
STAT News
On this week’s episode of “The Readout LOUD”: Why have so many Americans lost trust in science? And how have our policy leaders fueled that mistrust? We speak to STAT’s new trust-in-science reporter Nicholas Florko about the impact of…
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3 takeaways from a European obesity scientific meeting
BioPharma Dive
Eli Lilly impressed with its amylin-Zepbound combination data. Elsewhere, Novo demonstrated continued weight loss following a switch to oral and AbbVie and Boehringer gave glimpses into their contenders.
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As CDC redesigns annual health survey, it removes questions about disabilities
STAT News
A proposed redesign of the federal government’s annual health survey would result in significant undercounting of Americans with intellectual and developmental disabilities, according to advocates for the vulnerable population. The…
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Lilly, Foghorn part ways; Wave’s FDA-approved plans
BioPharma Dive
The pharma giant cut its partnership after a cancer drug disappointed in testing. Elsewhere, Teva and Samsung Bioepis expanded a partnership and space biotech Varda brought in $251 million.
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Sanofi, Regeneron broaden alliance to find their next Dupixent
BioPharma Dive
The deal carries a $1 billion upfront payment and tasks the two companies to develop long-acting antibody drugs that go after the same targets as their blockbuster anti-inflammation agent.
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STAT+: A journey to witness China’s biotech boom up close
STAT News
Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. I am newly enamored with Hans Zinsser , a Harvard bacteriologist who in 1935 wrote “Rats, Lice and History,” a…
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HHS kicks off new programs to speed clinical trials as Chinese competition looms
BioPharma Dive
The department is offering funding to teams with innovative proposals as it considers ending the traditional phased clinical trial system.
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Pfizer’s eczema drug clears skin in mid-stage trial
BioPharma Dive
Detailed results are competitive with Dupixent and Ebglyss, but the drug lacks differentiation amid an increasingly competitive landscape, one analyst argued.
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STAT+: MAHA goes corporate
STAT News
You’re reading the web edition of D.C. Diagnosis, STAT’s twice-weekly newsletter about the politics and policy of health and medicine. Sign up here to receive it in your inbox on Tuesdays and Thursdays. Michigan Democratic Senate candidate…
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STAT+: A major insurer on how it may replicate Medicare’s chronic-care experiment
STAT News
Y ou’re reading the web edition of STAT’s Health Tech newsletter, our guide to how technology is transforming the life sciences. Sign up to get it delivered in your inbox every Tuesday and Thursday. Blue Shield of California is one of 17…
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STAT+: Pharmalittle: We’re reading about a plan to lower Medicare drug prices, a Lilly obesity drug, and more
STAT News
Top of the morning to you. Gray skies are hovering over the Pharmalot campus right now, but our spirits remain sunny, nonetheless. Why? We will trot out a bit of insight from the Morning Mayor, who would advise that “Every new day should…
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The Real Gap in All of Us Isn’t Consent, It’s Conversion
MedCity News
Why more than 300,000 missing patient records reveal an engineering problem, not a policy one — and why that’s good news. The post The Real Gap in All of Us Isn’t Consent, It’s Conversion appeared first on MedCity News .
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5 FDA decisions to watch in the fourth quarter of 2026
BioPharma Dive
The next three months will feature anticipated decisions on a new kind of cancer immunotherapy, as well as medicines important to the futures of Roche, GSK and Gilead.
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Trump administration appeals ruling blocking limits on international student visas
STAT News
Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds. Sign up here . Happy October! Lots of stories! You’re going to love them! Read the rest… © APStock
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STAT+: Invivyd’s pursuit of a Covid vaccine alternative gets a lift, but an FDA hurdle may await
STAT News
This story first appeared in Adam’s Biotech Scorecard, a STAT newsletter. Sign up here to get it delivered to your inbox. And subscribe to STAT+ to get an unabridged version, with exclusive content. An update on Invivyd, the small biotech…
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STAT+: Why a Huntington’s patient isn’t fazed by the waning effect of UniQure’s gene therapy
STAT News
This story first appeared in Adam’s Biotech Scorecard, a STAT newsletter. Sign up here to get it delivered to your inbox. And subscribe to STAT+ to get an unabridged version, with exclusive content. Lauren Holder is an advocate for the…
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STAT+: Two key Senate health committees face major shake-ups
STAT News
WASHINGTON — The upcoming midterm elections are setting the stage for unusually significant changes to key Senate committees that play an important role in health care. Both the finance and health committees could undergo major changes…
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STAT+: Can a top Republican from a bygone political era fix pharma’s woes in Washington?
STAT News
WASHINGTON — Eric Cantor has been here before. In 2013, the House Republican, who had become the party’s de facto “chief political strategist,” was at a Virginia resort with his colleagues, working to shift the GOP away from its stereotype…
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STAT+: In Shanghai’s ‘Science City,’ China’s ascendant biotechs make their pitch to the world
STAT News
SHANGHAI — The biotech executives appeared triumphant. It was a balmy, overcast Sunday here in the glimmer-and-glass “Science City” district, and the four leaders were on stage at the ballroom level of the five-star Hilton, joking about…
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Opinion: Claude analyzed my genome in 30 minutes. Now we need standards for the results
STAT News
Unpacking from vacation a couple months back, I decided to give artificial intelligence a task. I paused folding my laundry, sat down with Claude, and asked it to analyze the entirety of my genome. Back in 2009, this was a task that quite…
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Opinion: I studied GLP-1 use in children. The results are reassuring
STAT News
I am a transplant surgeon, and my patients are getting younger . Many are in their 30s and 40s — adults whose organ failure can be traced back to childhood obesity. And obesity itself can be a barrier to transplant , compounding the crisis…
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STAT+: Sanofi, Regeneron expand partnership after Dupixent success
STAT News
Sanofi and Regeneron Pharmaceuticals, the duo behind the hugely successful drug Dupixent, are re-upping their partnership, with the companies announcing Thursday an expanded collaboration on a new series of antibodies for immunological…
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Derandomizing Dense Binary Hypervector Codebooks for Quantized Scalars
arXiv cs.NE (Neural／Bio)
arXiv:2609.38471v1 Announce Type: cross Abstract: Hyperdimensional computing and vector symbolic architectures often represent quantized scalar levels by dense binary codebooks whose level-to-level similarity is intended to follow a…
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How much of fly walking is written in the wiring?
arXiv cs.NE (Neural／Bio)
arXiv:2609.38665v1 Announce Type: new Abstract: Connectome models of the fly nerve cord generate walking-like motor rhythms, but oscillation alone does not show that the specific wiring matters. Here we provide, to our knowledge, the first…
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Null-model treatment of the sensory-motor boundary changes an evolutionary connectome comparison
arXiv cs.NE (Neural／Bio)
arXiv:2609.39248v1 Announce Type: new Abstract: Randomised copies of a connectome are the usual baseline for asking whether measured wiring matters, and the answer depends on what the randomisation preserves. We evolved embodied foraging…
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Novelty Search with Cross-Task Collaborative Discovery
arXiv cs.NE (Neural／Bio)
arXiv:2607.00761v3 Announce Type: replace Abstract: Novelty Search (NS) promotes exploration by rewarding behaviorally novel solutions rather than directly optimizing predefined objectives, making it particularly useful when objective…
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Self-Evolving Algorithm-Design Agents: Escaping In-Context Evolutionary Stagnation via Population-Curated Policy Optimization
arXiv cs.NE (Neural／Bio)
arXiv:2609.38757v1 Announce Type: cross Abstract: Large language models are increasingly participating in complex real-world tasks in the form of algorithm-design agents, designing and refining algorithms. Many successful algorithm-design…
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Large Language Model-Guided Evolutionary Discovery of Native Neural Architectures for Spiking Sequence Modeling
arXiv cs.NE (Neural／Bio)
arXiv:2609.40258v1 Announce Type: new Abstract: Spiking neural networks (SNNs) offer low-energy sequence modeling through sparse, event-driven computation. However, interactions among spike encoding, neuronal dynamics, and information…
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Evolutionary foraging in grids: Intermittent search dynamics emerge in finite, depletable landscapes
arXiv cs.NE (Neural／Bio)
arXiv:2609.39239v1 Announce Type: cross Abstract: How search strategies evolve in finite, depletable landscapes remains a question in foraging theory. We study this problem with an evolutionary simulation in which agents forage on a…
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Simulating Synchrony Loop Networks in the Open Source RISP Neuroprocessor
arXiv cs.NE (Neural／Bio)
arXiv:2609.38432v1 Announce Type: new Abstract: Neuromorphic spiking neural networks (SNNs) offer a promising alternative to conventional deep neural networks for tasks with computational resource or data constraints. However, their…
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Behavioral Persistence and Incomplete Functional Transfer of Co-evolved Communication in Evolutionary Robotics
arXiv cs.NE (Neural／Bio)
arXiv:2609.38527v1 Announce Type: cross Abstract: This work evaluates the direct transfer of a co-evolved communication protocol from a 2D simulation to a 3D physical environment, without retraining the network weights. Two e-puck-type…
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Fairness-Aware Performance Evaluation for Multi-Party Multi-Objective Optimization
arXiv cs.NE (Neural／Bio)
arXiv:2601.22497v2 Announce Type: replace Abstract: In multiparty multiobjective optimization problems, solution sets are usually evaluated using classical performance metrics, aggregated across DMs. However, such mean-based evaluations…
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T-Router: Learning Thalamic Routing for Reasoning with Parameter-Efficient Reinforcement Learning
arXiv cs.NE (Neural／Bio)
arXiv:2609.39109v1 Announce Type: cross Abstract: Parameter-efficient reinforcement learning aims to improve reasoning with a compact trainable interface to a pretrained model. We introduce the Thalamic Router (T-Router), which…
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Beyond Missing Rates: Rethinking Incomplete Multi-View Clustering with Protocol Divergence
arXiv cs.NE (Neural／Bio)
arXiv:2606.04857v3 Announce Type: cross Abstract: Incomplete multi-view clustering (IMVC) is typically evaluated by retraining separate models under different missing-view configurations. Evaluations indexed only by nominal missing rate…
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From DNA Design to DNA Slimming: Auditable Agentic Discovery of a Deletion-Only Designer
arXiv cs.NE (Neural／Bio)
arXiv:2609.40143v1 Announce Type: cross Abstract: Compact regulatory DNA can free up space in vector payloads, reduce synthesis and assay burden, and expose which sequence features drive predicted activity. Yet most model-based…
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Multi-Depth Temporal Fusion for Feedforward, Locally Trained Spiking Neural Networks
arXiv cs.NE (Neural／Bio)
arXiv:2609.37047v2 Announce Type: replace Abstract: We propose a new spiking neural network (SNN) design to process static images and event streams using time-to-first-spike (TTFS) latencies. Our key research question is which…
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An Island-Based Parallel Biased Random-Key Genetic Algorithm for the Three-Dimensional Trailer Loading Problem
arXiv cs.NE (Neural／Bio)
arXiv:2609.39272v1 Announce Type: new Abstract: The Three-Dimensional Trailer Loading Problem (3D-TLP) involves determining the optimal placement and orientation of heterogeneous items within the confined space of a trailer while…
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Deep learning perturbation models can outperform baselines on calibrated metrics
Nature Biotechnology
Nature Biotechnology, Published online: 01 October 2026; doi:10.1038/s41587-026-03307-w Calibration-aware evaluation of perturbation models shows that deep learning models can outperform baselines.